Having a knowledge of all of the two-letter words will greatly improve your Scrabble gameplay, either when you need to build off an existing tile to form a new word, or at the end of the game when you have two or three tiles left and need to dump them off as quickly as possible. Two-letter words are also very useful when playing a new word parallel (alongside, above, or beneath) to an existing word.
By knowing words with prefixes and suffixes, you'll be able to piggyback off of your opponents' scores.
Common examples for suffixes include S, -ED, -ER, -ING, -LY, -ENT, -IEST, -FUL, -ITY, -NESS, -CY, -AL, -TION, -ITE in addition to prefixes NON-, EX-, TRI-, PRE-, and MIS-.
For example, if you add the suffix "ER" to "JUMP," you can make the word "JUMPER." Or if your opponent played the word "VERBAL," you can add the prefix "NON" to make "NONVERBAL" and rack up points.
These prefixes and suffixes can also be handy to make Bingo and get the 50 point bonus.
The letters A, E, I, L, N, R, S, and T are some of the most commonly used letters in the English alphabet. If you're having a rough time coming up with words, having one or more of these letters on your deck can help greatly.
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They really help